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Gerhard Domagk [1895-1964] German
Rank: 102
Scientist


Gerhard Johannes Paul Domagk was a German pathologist and bacteriologist. He is credited with the discovery of Sulfonamidochrysoidine – the first commercially available antibiotic – for which he received the 1939 Nobel Prize in Physiology or Medicine.

Medical



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The problem of chemotherapy of bacterial infections could be solved neither by the experimental medical research worker nor by the chemist alone, but only by the two together working in very close cooperation over many years. Medical
101
Whatever contributes to the preservation of life is good; all that destroys life is evil.
102
We all remember how, at the beginning of the sulphonamide era, it was repeatedly observed that fresh cases of gonorrhoea in men responded best to sulphonamide treatment when suppuration had already occurred for several days, and not at the first appearance of the disease.
103
Why some gonococcal strains are more resistant than others is still not clear.
104
A rise in body temperature during sulphonamide treatment intensifies the biochemical reaction between drug and pathogen, while at the same time the heat itself injures the heat-sensitive gonococci.
105

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